Characterization of sulfhydryl heterogeneity in human serum albumin and recombinant human serum albumin for clinical use |
| |
Authors: | Ikegaya Kazuo Nokihara Kiyoshi Yasuhara Tadashi |
| |
Institution: | Advanced Medical Research Laboratory, Mitsubishi Tanabe Corp., Osaka, Japan. k.i.1203peace-man@tenor.ocn.ne.jp |
| |
Abstract: | Since human serum albumin has one sulfhydryl group and 17 disulfides, reactive sulfhydryl groups give rise to heterogeneity. The present paper presents a comparison of sulfhydryl heterogeneity in human serum albumin and recombinant human serum albumin for clinical use. Low molecular weight sulfhydryl compounds were identified from both sources. The recombinant albumin had a much higher sulfhydryl content than plasma serum albumin. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|