Solid-phase synthesis of oligonucleotides containing a bipyridine ligand at the 3'-3' inversion of polarity site |
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Authors: | Galeone A Mayol L Oliviero G Rigano D Varra M |
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Affiliation: | Dip. di Chimica delle Sostanze Naturali, Univ. di Napoli Federico II, Italy. |
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Abstract: | The preparation of a solid support useful for the synthesis of oligonucleotides with a 3'-3' inversion of polarity, via a linker containing a chelating molecule, namely 2,2'-bipyridine, is described. |
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