Human puromycin-sensitive aminopeptidase: cloning of 3' UTR, evidence for a polymorphism at a.a. 140 and refined chromosomal localization to 17q21. |
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| Authors: | W O Bauer I Nanda G Beck M Schmid F Jakob |
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| Affiliation: | Department of Metabolism, Endocrinology and Molecular Medicine, Medizinische Poliklinik, Würzburg, Germany. |
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| Abstract: | Puromycin-sensitive aminopeptidase is a predominantly cytoplasmatic zinc-dependent exopeptidase. Its physiological function is not known to date. Here we report data on tissue distribution, a polymorphism within the coding region and the complete 3' UTR. The gene (NPEPPS alias PSA) was physically mapped to chromosome 17q21.2-->q21.32 using fluorescence in situ hybridization. |
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