THE ACCELERATION OF SAPONIN HEMOLYSIS BY PROFLAVINE |
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Authors: | H. Bruce Collier |
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Affiliation: | From the Department of Biochemistry, Dalhousie University, Halifax, N.S. |
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Abstract: | Proflavine is a very powerful accelerator of saponin hemolysis of rabbit, human, and dog erythrocytes. Lysolecithin hemolysis, on the other hand, is inhibited. Dog erythrocytes in the presence of proflavine undergo marked changes in shape, finally becoming rods of about 13 µ in length. Rabbit and human erythrocytes are not altered in form under these conditions. |
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