Mismatch repair: the praying hands of fidelity |
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| Authors: | Jiricny J |
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| Institution: | Institute of Medical Radiobiology of the University of Zürich and the Paul Scherrer Institute, August Forel-Strasse 7, CH-8008, Zürich, Switzerland. jiricny@imr.unizh.ch |
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| Abstract: | High-resolution crystal structures have recently been solved for the mismatch binding protein MutS of Escherichia coli and its Thermus aquaticus homologue; they show how these factors recognise such structurally diverse substrates as base-base mismatches and insertion/deletion loops. |
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