A two-component response regulator, gltR, is required for glucose transport activity in Pseudomonas aeruginosa PAO1. |
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Authors: | A E Sage W D Proctor and P V Phibbs Jr |
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Abstract: | A 729-bp open reading frame (gltR) was identified in Pseudomonas aeruginosa PAO1 that encodes a product homologous to the two-component response regulator family of proteins. Disruption of gltR caused loss of glucose transport activity. Restoration of gltR resulted in wild-type levels of glucose transport. These findings indicate that gltR is required for expression of the glucose transport system in P. aeruginosa. |
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