Catalase activity in human erythrocytes: effect of phenoxyherbicides and their metabolites |
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Authors: | Bukowska B Chajdys A Duda W Duchnowicz P |
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Affiliation: | Department of Biophysics and Environmental Pollution, University of Lódz, Banacha 12/16, Lódz, 90-237, Poland. bukow@biol.uni.lodz.pl |
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Abstract: | The effects of exposure to different concentrations of phenoxyherbicides and their metabolites were studied in human erythrocytes, with particular attention to catalase (CAT-EC. 1.11.1. 6- hydrogen peroxide: hydrogen peroxide oxidoreductase). 4-chloro-2-methylphenoxyacetic acid (MCPA), 2,4-dimethylphenol (2, 4-DMP) and 2,4-dichlorophenoxyacetic acid (2,4-D) did not affect CAT activity, but 2,4-dichlorophenol (2,4-DCP) and 2,4,5-trichlorophenol (2,4,5-TCP) decrease its activity, the latter being the more inhibitory. |
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Keywords: | catalase 2,4‐dichlorophenoxyacetic acid (2,4‐D) 4‐chloro‐2‐methylphenoxyacetic acid (MCPA) 2,4‐dichlorophenol (2,4‐DCP) 2,4,5‐trichlorophenol (2,4,5‐TCP) 2,4‐dimethylphenol (2,4‐DMP) |
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