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Differential response of linear and angular psoralens in PUVA-induced apoptosis in HL-60 cells.
Authors:Giampietro Viola  Laura Facciolo  Daniela Vedaldi  Silvia Disarò  Giuseppe Basso  Francesco Dall'Acqua
Affiliation:Department of Pharmaceutical Sciences, University of Padua, via Marzolo 5, 35131 Padua, Italy. giampietro.viola.1@unipd.it
Abstract:Treatment of cells with UVA radiation in combination with linear psoralens induces a cell-cycle block and subsequent apoptosis, whereas angular derivatives produce apoptosis without affecting the cellular cycle.
Keywords:
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