Comparison of Borrelia isolated from UK foci of Lyme disease |
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| Authors: | M. Anne Livesley Ian P. Thompson Paul B. Rainey Patricia A. Nuttall |
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| Affiliation: | NERC Institute of Virology and Environmental Microbiology, Mansfield Road, Oxford OX1 3SR, UK; Department of Plant Sciences, University of Oxford, South Parks Road, OxfordOX1 3RB, UK |
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| Abstract: | Abstract Restriction endonuclease digestion of linear borrelial chromosomal DNA showed that three isolates of UK Lyme disease spirochaetes differed markedly from each other and from published data for other isolates from North America and continental Europe. Analysis of linear plasmid bands revealed that UK isolates differed from each other in the number and sizes of the plasmids in isolates from different foci of UK Lyme disease. Fatty acid analysis (of fatty acid methyl ester (FAME) profiles) showed the UK isolates clustering together with the relapsing fever spirochaetes, Borrelia turicatae and Borrelia parkeri . These data are discussed in respect of current knowledge of Lyme borreliosis in the UK. |
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| Keywords: | Borrelia burgdorferi Lyme borreliosis |
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