Population studies on the inter-α-trypsin inhibitor (ITI) polymorphism

Serum samples from four European populations — Germans from Jena, Germans from Hannover, Italians from Udine, and Slovakians from Bratislava — were tested for the inter-α-trypsin inhibitor (ITI) polymorphism. The results are compared with those reported for other European, Asiatic and African populations. Reviewing all the hitherto published ITI allele frequencies one can see that the variability among European Populations seems to be rather small, whereas Asiatic and African populations are striking by quite different distribution patterns.