Fructose as a carbohydrate source yields stable pH and redox parameters in microcarrier cell culture |
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Authors: | Toshiko Imamura Charles L Crespi William G Thilly Henri Brunengraber |
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Institution: | Department of Nutrition and Food Science, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139 USA |
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Abstract: | The pH and cytosolic NADH/NAD+ redox potential in microcarrier cultures of Madin-Darby canine kidney cells remain within physiological range when fructose is substituted for glucose in medium formulation. This difference is accounted for by the low rate of lactic acid production in cultures utilizing fructose as a primary carbohydrate source. |
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Keywords: | To whom correspondence should be addressed |
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