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The glycoprotein P0 in peripheral gliogenesis
Authors:Lukas Sommer  U. Suter
Affiliation:Institute of Cell Biology, Swiss Federal Institute of Technology, ETH-H?nggerberg, CH-8093 Zürich, Switzerland Tel.: +41–1–633–3432; Fax: +41–1–633–1190; E-mail: usuter@cell.biol.ethz.ch, CH
Abstract:Recent data show that during development protein zero, P0, the most abundant peripheral nerve myelin protein, is detecable long before myelination. In particular, the expression of P0 in a fraction of migrating neural crest reveals progenitor cell heterogeneity in the developing PNS. Here we review the regulation and potential function of P0 during peripheral gliogenesis.
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