Catalytic antibodies (abzymes) induced by stable transition-state analogs |
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| Authors: | Nevinsky G A Semenov D V Buneva V N |
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| Affiliation: | Novosibirsk Institute of Bioorganic Chemistry, Siberian Division of the Russian Academy of Sciences, Novosibirsk, 630090, Russia. Nevinsky@niboch.nsc.ru |
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| Abstract: | This review deals with recent advances in the generation of catalytic antibodies by the immunization of animals with stable transition-state analogs. Characteristic features in the functioning of such abzymes are considered in comparison with traditional enzymes. |
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