Mutagenic effect of new chemical compounds. IV. Mutagenic effect of dialkylaminoethyl esters of 5,6-dihydro-7H-benz(c)carbazol-carboxylic acids] |
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Authors: | G M Paronikian L G Akopian G A Dabrinian E A Tumasian |
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Abstract: | The mutagenic effect of dialkylaminoet hyl esters of 5,6-dihydro-7H-benz(c)carbazole-carboxylic acids on biochemical mutants (Escherichia coli P-678, Actinomyces rimosus 222) is found. Hydrochloride of diethylaminoethyl ester of 5,6-dihydro-7H-benz(c)carbazole-9-carboxylic acid, which induced reversible and direct mutations, proved to be the most active compound, its mutagenic activity exceeding considerably the activity of ethylene imine. |
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