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Genetically variant human pluripotent stem cells selectively eliminate wild-type counterparts through YAP-mediated cell competition
Affiliation:1. Department of Biomedical Science, University of Sheffield, Western Bank, Sheffield S10 2TN, UK;2. Neuroscience Institute, University of Sheffield, Western Bank, Sheffield S10 2TN, UK;3. Department of Automatic Control and Systems Engineering, University of Sheffield, Mappin Street, Sheffield S1 3JD, UK;4. National Heart and Lung Institute, Imperial Centre for Translational and Experimental Medicine, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK
Abstract:
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  • Keywords:human pluripotent stem cells  culture-acquired variants  cell competition  YAP
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