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Gene copy-number changes and chromosomal instability induced by aneuploidy confer resistance to chemotherapy
Affiliation:1. Department of Experimental Oncology at IEO, European Institute of Oncology IRCCS, Via Adamello 16, 20139 Milan, Italy;2. European Research Institute for the Biology of Ageing, University of Groningen, University Medical Center Groningen, 9713 AV, Groningen, the Netherlands;3. Institut Curie, PSL Research University, CNRS, UMR144, Paris, France;4. Department of Human Molecular Genetics and Biochemistry, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel;5. Department of Oncology and Hemato-Oncology, University of Milan, Via Santa Sofia 9/1, 20122 Milan, Italy
Abstract:
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  • Keywords:aneuploidy  cancer  genome instability  chemotherapy  drug resistance
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