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IL-33 causes thermogenic failure in aging by expanding dysfunctional adipose ILC2
Affiliation:1. Department of Physiology, University of California, San Francisco, San Francisco, CA, USA;2. Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA;3. Department of Comparative Medicine, Yale School of Medicine, New Haven, CT, USA;4. Department of Biochemistry, Molecular Biology, and Molecular Biophysics, University of Minnesota, Minneapolis, MN, USA;5. Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA;6. Yale Center for Research on Aging, Yale University, New Haven, CT, USA
Abstract:
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  • Keywords:aging  adipose  ILC2  thermogenesis  IL-33  metabolism  inflammation
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