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Epigenetic modification of Nrf2 in 5-fluorouracil-resistant colon cancer cells: involvement of TET-dependent DNA demethylation
Authors:K A Kang  M J Piao  K C Kim  H K Kang  W Y Chang  I C Park  Y S Keum  Y J Surh  J W Hyun
Affiliation:1.School of Medicine, Jeju National University, Jeju, Korea;2.Division of Radiation Cancer Research, Korea Institute of Radiological and Medical Sciences, Seoul, Korea;3.Department of Biochemistry, College of Pharmacy, Dongguk University, Goyang, Korea;4.Tumor Microenvironment Global Core Research Center and Cancer Research Institute, Seoul National University, Seoul, Korea
Abstract:
Keywords:colon cancer cells   5-fluorouracil resistance   epigenetic modification   DNA demethylase   Nrf2   oxidative stress
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