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A blood analog for laser-induced photochemical anemometry
Affiliation:1. Biofluid Mechanics Laboratory, Department of Civil Engineering, University of Utah, 3220 MEB, Salt Lake City, Utah 84112, USA;2. Commercial Chemistry, Salt Lake City, Utah 84121, USA;3. Physiological Transport Studies Laboratory, Department of Chemical Engineering, The Pennsylvania State University, University Park, PA 16802, USA;1. College of Chemistry and Materials Science, Huaibei Normal University, Huaibei, Anhui 235000, China;2. Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, China;3. Department of Chemistry and Biochemistry, Utah State University, Logan, Utah 84322-0300, USA;1. Program in Nano Science and Technology, Graduate School of Convergence Science and Technology, Seoul National University, 145 Gwanggyo-ro, Yeongtong-gu, Suwon–si, Gyeonggi-do, 443-270, Republic of Korea;2. Advanced Institutes of Convergence Technology, 145 Gwanggyo-ro, Yeongtong-gu, Suwon–si, Gyeonggi-do, 443-270, Republic of Korea;3. Center for Nanoparticle Research, Institute for Basic Science (IBS), Republic of Korea
Abstract:A transparent viscoelastic blood analog fluid was developed for use with Laser-Induced Photochemical Anemometry. To provide solubility of the photochemical tracer, 1′, 3′, 3′-trimethyl-6-nitroindoline-2-spiro-2-benzopyran (TNSB dye, Kodak Chemicals), the analog solvent needed to be nonpolar, thus currently available aqueous blood analogs were not suitable. An analog consisting of 0.04% ethylhydroxyethylcellulose dissolved in gamma-butyrolactone produced a pseudoplastic steady shear response with low elasticity in unsteady shear, while being compatible with the photochemical tracer.
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