Lipid composition, lipid fluidity and radioresistance of Deinococcus radiodurans and two mutant strains |
| |
Authors: | Dani le Montaudon, Marie-Annette Carbonneau, Anne-Marie Melin,Nicole Rebeyrotte |
| |
Affiliation: | Laboratoire de Biochimie Médicale A, Université de Bordeaux II, France. |
| |
Abstract: | The lipid composition of D. radiodurans strain R1 and of two mutant strains has been studied in relation to membrane fluidity and sensitivity to X-ray radiation. No significant difference in the unsaturation degree of fatty acids was found between parental and mutant strains. An important decrease of carbohydrate-containing lipids was observed in the radiosensitive mutant strain. We also observed a higher fluidity in both mutant strains than in the parental one. Modification of membrane lipid fluidity by growing the parental strain at 39 degrees C did not lead to modified radioresistance. These results suggest that a particular chemical composition of the membrane leading to a special lipid phase may be an important parameter in controlling radiosensitivity. |
| |
Keywords: | carbohydrate-containing lipids membrane fluidity radioresistance D. radioduransAuthor Keywords: lipides glycosylé s fluidité membranaire radioré sistance D. radiodurans |
本文献已被 ScienceDirect 等数据库收录! |