The Role of Notch Signaling in Adult Neurogenesis |
| |
| Authors: | Itaru Imayoshi Ryoichiro Kageyama |
| |
| Institution: | (1) Institute for Virus Research, Kyoto University, Shogoin-Kawahara, Sakyo-ku, Kyoto 606-8507, Japan;(2) The Hakubi Center, Kyoto University, Kyoto 606-8507, Japan;(3) Japan Science and Technology Agency, Precursory Research for Embryonic Science and Technology (PRESTO), Kyoto 606-8507, Japan;(4) Japan Science and Technology Agency, Core Research for Evolutional Science and Technology (CREST), Kyoto 606-8507, Japan |
| |
| Abstract: | Neurogenesis occurs throughout adulthood in the mammalian brain. Newly born neurons are incorporated into the functional networks
of both the olfactory bulb and the hippocampal dentate gyrus, and there is growing evidence that adult neurogenesis is important
for various brain functions. Continuous neurogenesis is achieved by the coordinated proliferation and differentiation of adult
neural stem cells. In this review, we discuss the recent findings concerning the roles of Notch signaling in adult neural
stem cells. |
| |
| Keywords: | |
| 本文献已被 PubMed SpringerLink 等数据库收录！ |
|
