Lesions induced by complement in vitro on the protoscoleces of Echinococcus multilocularis: a study by electron microscopy. |
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Authors: | A I Kassis S L Goh C E Tanner |
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Affiliation: | Institute of Parasitology, Macdonald College, McGill University, Province of Quebec, Canada H0A 1C0 |
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Abstract: | Changes in the ultrastructure of the tegument of Echinococcus multilocularis protoscoleces during complement-mediated lysis in vitro was studied using transmission and scanning electron microscopy. It was found that the total disintegration of protoscoleces by complement proceeds through formation of ‘tegumental bubbles’ and disruption of the external plasma membrane. This sequence of events was evident in the appearance of numerous loose membrane fragments and vesicles, the lifting of the external unit membrane of the microtriches and the release of organelles from the distal cytoplasm. Subsequent events, such as the appearance of a ‘fuzzy’ coat and disruption of the basement membrane, were probably due to autolysis. |
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Keywords: | Cestoda hydatid protoscoleces complement proteins lysis tegument ultrastructure transmission electron microscopy scanning electron microscopy tegumental bubbling membrane lesions microtriches |
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