Sequence polymorphisms, allelic expression status and chromosome locations of the chicken IGF2 and MPR1 genes |
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| Authors: | Yokomine T Kuroiwa A Tanaka K Tsudzuki M Matsuda Y Sasaki H |
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| Institution: | Division of Human Genetics, National Institute of Genetics, Graduate University for Advanced Studies, 1-111 Yata, Mishima 411-8540, Japan. |
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| Abstract: | By screening 26 chicken breeds and lines, DNA polymorphisms were identified in the IGF2 and MPR1 genes, of which mammalian homologues are parentally imprinted, and the GAPD gene, a housekeeping control. Using the polymorphisms as genetic markers, we found that all three genes are expressed biallelically in embryonic tissues. IGF2 and MPR1 were mapped on chicken chromosomes 5 and 3, respectively, by fluorescence in situ hybridization, demonstrating conserved linkage homology between mammals and birds. |
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