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Azalide 3,6-ketals: antibacterial activity and structure-activity relationships of aryl and hetero aryl substituted analogues |
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| Authors: | Sakya Subas M Bertinato Peter Pratt Bryan Suarez-Contreras Melani Lundy Kristin M Minich Martha L Cheng Hengmiao Ziegler Carl B Kamicker Barbara J Hayashi Shigeru F Santoro Sheryl L George David M Bertsche Camilla D |
| Affiliation: | Veterinary Medicine Research and Development, Pfizer Inc, Groton, CT 06340, USA. sakyas@groton.pfizer.com |
| Abstract: | Aryl and hetero aryl substituted 3,6-ketals of 15-membered azalide analogues were synthesized and were found to have potent in vitro antibacterial activity against veterinary pathogens, including Staphylococcus aureus and Pasteurella multocida. |
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