| 图论方法研究蛋白质结构预测问题 |
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| 引用本文： | 史晓红,刘文斌,王燕,罗亮,许进.图论方法研究蛋白质结构预测问题[J].生物技术,2005,15(5):89-92. |
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| 作者姓名： | 史晓红 刘文斌 王燕 罗亮 许进 |
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| 作者单位： | 华中科技大学自动控制科学与系统工程系,湖北,武汉,430074 |
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| 基金项目： | 国家自然科学基金资助项目（No.60274026;60403002;60373089） |
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| 摘 要： | 图论方法在蛋白质结构预测中占有重要地位。该文简要介绍图的连通子图、图的最大团、图的完美匹配及图谱法在蛋白质结构预测中的应用。对国内外近年来应用这些方法在蛋白质3D结构预测及折叠的研究工作进行了回顾，并分析、比较了这几种方法的效果和特点。
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| 关 键 词： | 图的连通子图 最大团 完美匹配 图谱法 蛋白质结构预测 |
| 文章编号： | 1004-311X（2005）05-0089-04 |
| 收稿时间： | 2005-03-31 |
| 修稿时间： | 2005-07-12 |
Application of Graph Theory Methods to Protein Structure Prediction |
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| SHI Xiao-hong,LIU Wen-bin,WANG Yan,LUO Liang,XU Jin.Application of Graph Theory Methods to Protein Structure Prediction[J].Biotechnology,2005,15(5):89-92. |
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| Authors: | SHI Xiao-hong LIU Wen-bin WANG Yan LUO Liang XU Jin |
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| Institution: | Department of Control Science and Engineering, Huazhong University of Sciences and Technology, Wuhan 430074, China |
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| Abstract: | Graph theory methods have great importance in the field of prediction of protein structure. The paper briefly introduces some graph theory methods such as maximal connected subgraph, maximal cliques, perfect match and graph spectral research which applied in prediction of protein structure. Recently it applied on the problem of protein folding and 3D structure prediction using these methods are then reviewed. The effect and feature of these methods are also analyzed and compared. |
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| Keywords: | maximal connected subgraph maximal cliques perfect match graph spectral research mtein structure prediction |
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