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海南石斛化学成分研究
引用本文:张友源,宋希强,梅文莉,左文健,蔡彩虹,程瑾,戴好富. 海南石斛化学成分研究[J]. 热带亚热带植物学报, 2015, 23(3): 317-322
作者姓名:张友源  宋希强  梅文莉  左文健  蔡彩虹  程瑾  戴好富
作者单位:1. 海南大学园艺园林学院, 海口 570228;2. 中国热带农业科学院热带生物技术研究所, 农业部热带作物生物学与遗传资源利用重点实验室, 海口 571101,海南大学园艺园林学院, 海口 570228,中国热带农业科学院热带生物技术研究所, 农业部热带作物生物学与遗传资源利用重点实验室, 海口 571101,中国热带农业科学院热带生物技术研究所, 农业部热带作物生物学与遗传资源利用重点实验室, 海口 571101,中国热带农业科学院热带生物技术研究所, 农业部热带作物生物学与遗传资源利用重点实验室, 海口 571101,北京林业大学生物科学与技术学院, 北京 100083,中国热带农业科学院热带生物技术研究所, 农业部热带作物生物学与遗传资源利用重点实验室, 海口 571101
基金项目:海南省产学研一体化专项资金(CXY20130044); 海南省普通高等学校研究生创新科研课题(2013 年, S09); 中西部高校提升综合实力计划(2013 年海南大学研究生联合培养项目)资助
摘    要:为了解海南石斛(Dendrobium hainanense Rolfe)的化学成分,采用色谱技术从海南石斛茎叶中分离得到14个化合物,经波谱分析分别鉴定为:2,6-二甲氧基对苯醌(1)、(+)-dehydrovomifoliol(2)、blumenol A(3)、2,7-二羟基-3,4-二甲氧基-9,10-二氢菲(4)、2,7-二羟基-3,4-二甲氧基菲(5)、3,7-二羟基-2,4-二甲氧基菲(6)、3-羟基-2,4,7-三甲氧基-9,10-二氢菲(7)、3-羟基-2,4,7-三甲氧基菲(8)、3,4,7-三羟基-2-甲氧基菲(9)、3,7-二羟基-2,4-二甲氧基-9,10-二氢菲(10)、(+)-lyoniresinol(11)、丁香脂素(12)、denchrysan A(13)和nobilone(14)。这些化合物均为首次从海南石斛中分离得到。活性测试结果表明化合物4~6、8~9、11和14对乙酰胆碱酯酶有抑制活性。

关 键 词:海南石斛  化学成分  
收稿时间:2014-09-25
修稿时间:2014-11-14

Chemical Constituents from Dendrobium hainanense (Orchidaceae) in Hainan
ZHANG You-yuan,SONG Xi-qiang,MEI Wen-li,ZUO Wen-jian,CAI Cai-hong,CHENG Jin and DAI Hao-fu. Chemical Constituents from Dendrobium hainanense (Orchidaceae) in Hainan[J]. Journal of Tropical and Subtropical Botany, 2015, 23(3): 317-322
Authors:ZHANG You-yuan  SONG Xi-qiang  MEI Wen-li  ZUO Wen-jian  CAI Cai-hong  CHENG Jin  DAI Hao-fu
Affiliation:1. Horticultural and Garden College, Hainan University, Haikou 570228, China;2. Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Academy of Tropical Agricultural Sciences, Haikou 571101, China,Horticultural and Garden College, Hainan University, Haikou 570228, China,Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Academy of Tropical Agricultural Sciences, Haikou 571101, China,Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Academy of Tropical Agricultural Sciences, Haikou 571101, China,Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Academy of Tropical Agricultural Sciences, Haikou 571101, China,College of Biological Sciences and Technology, Beijing Forestry University, Beijing 100083, China and Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Academy of Tropical Agricultural Sciences, Haikou 571101, China
Abstract:The aim was to understand the chemical constituents of Dendrobium hainanense. Fourteen compounds were isolated from its aerial parts by means of chromatographic techniques. On the basis of spectral data, they were identified as: 2,6-dimethoxy-p-benzoquinone (1), (+)-dehydrovomifoliol (2), blumenol A (3), erianthridin (4), nudol (5), 3,7-dihydroxy-2,4-dimethoxy-phenanthrene (6),3-hydroxy-2,4,7-trimethoxy-9,10-dihydrophenanthrene (7), 3-hydroxy-2,4,7-trimethoxy-9,10-dihydro-phenanthrene (8), 3,4,7-trihydroxy-2-methoxyphenanthrene (9), 3,7-dihydroxy-2,4-dimethoxy-9,10-dihydro-phenanthrene (10), (+)-lyoniresinol (11), (+)- syringaresinol (12), denchrysan A (13) and nobilone (14). All compounds were isolated from D. hainenense for the first time. Compounds 4-6, 8-9, 11 and 14 showed weak inhibitory activity against acetylcholinesterase.
Keywords:Dendrobium hainanense  Chemical constituent  Phenanthrene
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