How membrane proteins travel across the mitochondrial intermembrane space. |
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Authors: | C M Koehler S Merchant G Schatz |
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Affiliation: | Dept of Biochemistry, Biozentrum, University of Basel, CH-4056 Basel, Switzerland. |
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Abstract: | A newly discovered family of small proteins in the yeast mitochondrial intermembrane space mediates import of hydrophobic proteins from the cytoplasm into the inner membrane. Loss of one of these chaperone-like proteins from human mitochondria results in a disease that causes deafness, muscle weakness and blindness. |
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