Effects of 10-day long exposure to gamma irradiation at low doses on bone marrow cells in mice |
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| Authors: | Domaratskaia E I Starostin V I Tsetlin V V Bueverova E I Khrushchov N G |
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| Affiliation: | Institute of Developmental Biology, Russian Academy of Sciences, Moscow. edomar@proxima.idb.ac.ru |
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| Abstract: | Effects of ten day long exposure to gamma-irradiation at low doses (mean dose rate of 1.5-2.0 m Gy/day, total dose of 15 m Gy) on hemopoietic (CFU-S) and stromal (CFU-F) progenitor cells from murine bone marrow were examined. The CFU-F content measured as in vitro fibroblastic colony number showed 1.5-4.5-fold increase. Additionally, the size of ectopic marrow transplants evaluated by counting myelokariocytes and CFU-S numbers also increased. No significant changes of CFU-S proliferation rate were found. |
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