A subpopulation of adult skeletal muscle stem cells retains all template DNA strands after cell division期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

A subpopulation of adult skeletal muscle stem cells retains all template DNA strands after cell division

Authors:	Rocheteau Pierre Gayraud-Morel Barbara Siegl-Cachedenier Irene Blasco Maria A Tajbakhsh Shahragim

Affiliation:	Institut Pasteur, Stem Cells and Development, Department of Developmental Biology, CNRS URA 2578, 25 rue du Dr. Roux, Paris 75015, France.

Abstract:	Download : Download high-res image (335KB) Download : Download full-size image Highlights? Pax7^Hi quiescent stem cells constitute a metabolically low “dormant” subpopulation ? Both Pax7^Hi and Pax7^Lo quiescent stem cells are serially transplantable ? Only proliferating Pax7^Hi cells segregate old DNA strands to the renewing stem cell ? CO-FISH demonstrates that template DNA strand cosegregation engages all chromosomes

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