Protein targeting: entropy, energetics and modular machines |
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Authors: | Perry Andrew J Lithgow Trevor |
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Institution: | Department of Biochemistry and Molecular Biology, Bio21 Institute of Molecular Sciences and Biotechnology, University of Melbourne, Parkville, Australia. |
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Abstract: | New light is being shed on the mechanism of protein import into mitochondria. The inner membrane translocase can switch between modes of translocation, and assists what might be an entropic device to drive the initial entry of substrate proteins across the outer membrane. |
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