Cancer physics: diagnostics based on damped cellular elastoelectrical vibrations in microtubules |
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Authors: | Jiří Pokorný Clarbruno Vedruccio Michal Cifra Ondřej Kučera |
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Institution: | 1.Institute of Photonics and Electronics,Academy of Sciences of the Czech Republic,Prague 8,Czech Republic;2.COMSUBIN, Research Office,Italian Navy,La Spezia,Italy;3.Faculty of Electrical Engineering,Czech Technical University in Prague,Prague,Czech Republic |
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Abstract: | This paper describes a proposed biophysical mechanism of a novel diagnostic method for cancer detection developed recently
by Vedruccio. The diagnostic method is based on frequency selective absorption of electromagnetic waves by malignant tumors.
Cancer is connected with mitochondrial malfunction (the Warburg effect) suggesting disrupted physical mechanisms. In addition
to decreased energy conversion and nonutilized energy efflux, mitochondrial malfunction is accompanied by other negative effects
in the cell. Diminished proton space charge layer and the static electric field around the outer membrane result in a lowered
ordering level of cellular water and increased damping of microtubule-based cellular elastoelectrical vibration states. These
changes manifest themselves in a dip in the amplitude of the signal with the fundamental frequency of the nonlinear microwave
oscillator—the core of the diagnostic device—when coupled to the investigated cancerous tissue via the near-field. The dip
is not present in the case of healthy tissue. |
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