|
|||||
|
|
Emergent Group Dynamics Governed by Regulatory Cells Produce a Robust Primary T Cell Response |
|
| Authors: | Peter S. Kim Peter P. Lee Doron Levy |
| Affiliation: | 1.Department of Mathematics,University of Utah,Salt Lake City,USA;2.Division of Hematology, Department of Medicine,Stanford University,Stanford,USA;3.Department of Mathematics and Center for Scientific Computation and Mathematical Modeling (CSCAMM),University of Maryland,College Park,USA |
| Abstract: | The currently accepted paradigm for the primary T cell response is that effector T cells commit to autonomous developmental programs. This concept is based on several experiments that have demonstrated that the dynamics of a T cell response is largely determined shortly after antigen exposure and that T cell dynamics do not depend on the level and duration of antigen stimulation. Another experimental study has also shown that T cell responses are robust to variations in antigen-specific precursor frequency. |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ | |