Nuclear factor-kappa B localization and function within intrauterine tissues from term and preterm labor and cultured fetal membranes |
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| Authors: | Sonali Vora,Asad Abbas,Chong J Kim,Taryn LS Summerfield,Juan P Kusanovic,Jay D Iams,Roberto Romero,Douglas A Kniss,William E Ackerman Suffix" >IV |
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| Affiliation: | (1) Laboratory of Perinatal Research, Department of Obstetrics & Gynecology, College of Medicine, The Ohio State University, Columbus, OH, USA;(2) Perinatology Research Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA;(3) Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, MI, USA;(4) Department of Pathology, Wayne State University School of Medicine, Detroit, MI, USA;(5) Division of Maternal-Fetal Medicine, Department of Obstetrics & Gynecology, College of Medicine, The Ohio State University, Columbus, OH, USA;(6) Department of Biomedical Engineering, College of Engineering, The Ohio State University, Columbus, OH, USA |
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| Abstract: | Background The objective of this study was to quantify the nuclear localization and DNA binding activity of p65, the major transactivating nuclear factor-kappa B (NF-kappaB) subunit, in full-thickness fetal membranes (FM) and myometrium in the absence or presence of term or preterm labor. |
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