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Structure of the O-polysaccharide and serological studies of the lipopolysaccharide of Proteus mirabilis 2002
Authors:Perepelov Andrei V  Zab?otni Agnieszka  Shashkov Alexander S  Knirel Yuriy A  Sidorczyk Zygmunt
Institution:N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Prospect 47, 119991 Moscow, Russia.
Abstract:The structure of the O-polysaccharide of the lipopolysaccharide of Proteus mirabilis 2002 was elucidated by chemical methods and 1H and 13C NMR spectroscopy. It was found that the polysaccharide consists of branched pentasaccharide repeating units having the following structure: structure in text]. The O-polysaccharide of P. mirabilis 2002 has a common tetrasaccharide fragment with that of P. mirabilis 52/57 from serogroup O29, and the lipopolysaccharides of the two strains are serologically related. Therefore, based on the structural and serological data, we propose to classify P. mirabilis 2002 into the Proteus O29 serogroup as a subgroup O29a,29b.
Keywords:Proteus mirabilis  Lipopolysaccharide  O-polysaccharide structure  O-serogroup  Epitope  Serological classification
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