Chronic Helicobacter pylori infection does not significantly alter the microbiota of the murine stomach |
| |
Authors: | Tan Mai Ping Kaparakis Maria Galic Maja Pedersen John Pearse Martin Wijburg Odilia L C Janssen Peter H Strugnell Richard A |
| |
Institution: | Department of Microbiology and Immunology, University of Melbourne, Melbourne, Victoria 3010, Australia. |
| |
Abstract: | We examined the impact of Helicobacter pylori infection on the murine gastric microbiota by culture and terminal-restriction fragment length polymorphism and found that neither acute nor chronic H. pylori infection substantially affected the gastric microbial composition. Interestingly, the total H. pylori burden detected by real-time PCR was significantly higher than that revealed by viable counts, suggesting that the antigenic load sustaining H. pylori-induced gastritis could be considerably higher than previously believed. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|