Effects of caerulein + haloperidol on amphetamine-induced locomotor stereotypy in rats |
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Authors: | K Mueller J L Peel K L Rewey |
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Institution: | Department of Psychology, Texas Christian University, Fort Worth 76129. |
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Abstract: | The combination of haloperidol + caerulein has been reported to produce a long-lasting reduction of amphetamine-induced hyperlocomotions in rats. This study was designed to replicate those findings and to determine whether haloperidol + caerulein produce any unique effect on amphetamine-induced locomotor stereotypy. In two experiments, haloperidol + caerulein failed to produce a long-lasting reduction in amphetamine-induced hyperlocomotions. Although haloperidol reduced the locomotor stereotypy produced by higher doses of amphetamine, caerulein had no effect, either alone or combined with haloperidol. |
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