Dendritic morphogenesis |
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Authors: | Sarah McFarlane |
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Institution: | (1) Genes and Development Research Group, University of Calgary, Heritage Medical Research Building, Rm. 171, 3330 Hospital Dr., NW, T2N 4N1 Calgary, AB |
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Abstract: | Neurons are polarized cells with an axon and a dendritic arbor extending from the soma. Although the molecular mechanisms
underlying axon guidance are rapidly being elucidated, those that regulate the orientation, morphology, and elaboration of
dendritic processes are largely unknown. Several recent papers address these issues, and propose a set of molecular strategies
that control dendrite development. This review discusses these papers and what they reveal to us about how cell signaling
orchestrates neuronal form and connectivity during development. |
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Keywords: | Dendrite axon Trks cyclic nucleotides semaphorin neuronal polarity Notch |
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