Native and reconstituted chromosome fiber fragments |
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| Authors: | Günther F. Meyer Manfred Renz |
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| Affiliation: | (1) Max-Planck-Institut für Biologie, Abteilung Beermann, Spemannstr. 34, D 74 Tübingen, Federal Republic of Germany |
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| Abstract: | The structure of hen erythrocyte chromatin fibers was studied with the electron microscope. Chromatin fiber fragments with a length of about 5,000 Å and an average diameter of 320 Å are composed of 13 globular subunits (superbeads) which contain different numbers of nucleosomes. Their number average corresponds to 17 nucleosomes. — The interaction of lysine-rich histones with nucleosome chains was investigated by reconstitution experiments and was found to be semi-cooperative. |
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