首页 | 本学科首页   官方微博 | 高级检索  
   检索      


Circannual changes in the expression of vascular endothelial growth factor in the testis of roe deer (Capreolus capreolus)
Authors:Asja Wagener  Steffen Blottner  Frank Göritz  Wolf Jürgen Streich  Jörns Fickel
Institution:1. Breeding Biology and Molecular Genetics, Institute of Animal Sciences, Humboldt University of Berlin, Invalidenstr. 42, D-10115 Berlin, Germany;2. Department of Reproduction Biology, Leibniz-Institute for Zoo and Wildlife Research, Alfred-Kowalke-Str. 17, D-10315 Berlin, Germany;3. Department Reproduction Management, Leibniz-Institute for Zoo and Wildlife Research, Alfred-Kowalke-Str. 17, D-10315 Berlin, Germany;4. Department Evolutionary Genetics, Leibniz-Institute for Zoo and Wildlife Research, Alfred-Kowalke-Str. 17, D-10315 Berlin, Germany;1. School of Geosciences, The University of Edinburgh, King''s Buildings, West Mains Road, Edinburgh EH9 3JN, Scotland, UK;2. School of Biological and Biomedical Sciences, Durham University, Durham DH1 3LE, England, UK;3. School of Civil Engineering and Geosciences, Newcastle University, Newcastle upon Tyne NE1 7RU, England, UK;4. Geospatial Research Ltd., Department of Earth Sciences, Durham University, Durham DH1 3LE, England, UK;5. Department of Geography and Environment, Northumbria University, Ellison Building, Newcastle upon Tyne NE1 8ST, UK;1. Small Vertebrates’ Reproduction, Laboratory of Research on Arid Areas, Faculty of Biological Sciences, Houari Boumediene University of Sciences and Technology, El Alia, Algiers, Algeria;2. Mammal Ecophysiology, Laboratory of Research on Arid Areas, Faculty of Biological Sciences, Houari Boumediene University of Sciences and Technology, El Alia, Algiers, Algeria;3. University of Lyon, UMRS 449, Laboratory of General Biology, Catholic University of Lyon, Reproduction and Comparative Development/EPHE, Lyon Cedex 02, France
Abstract:Adult roe deer males show seasonal cycles of testicular growth and involution. The exact timing of these cycles requires endocrine regulation and local testicular control by autocrine/paracrine factors. Recent findings suggest that the vascular endothelial growth factor (VEGF) might have effects on both vascular and germinative cells in testis. Thus, we studied the expression pattern of vascular endothelial growth factor (VEGF) in roe deer testis using quantitative RT-PCR. The strength of VEGF mRNA expression depended on season. It reached its highest level at the peak of spermatogenesis during the pre-rutting period and had its nadir at the end of the rut when involution already began. The results suggested that VEGF may directly affect the regulation of spermatogenesis but may not be involved predominantly in testicular microvasculature as initially expected.
Keywords:
本文献已被 ScienceDirect 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号