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Von Hippel-Lindau tumor suppressor pathways & corresponding therapeutics in kidney cancer
Affiliation:1. State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai 200031, China;2. University of Chinese Academy of Sciences, Beijing 100049, China;3. Department of Medical Oncology, The First Affiliated Hospita, Hengyang MedicalSchool, University of South China, Hengyang, Hunan 421001, China;4. School of Life Science and Technology, Shanghai Tech University, Shanghai 200120, China;5. CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China;6. School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China;1. State Key Laboratory of Cell Biology, Chinese Academy of Sciences, Shanghai 200031, China;2. Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai 200031, China;3. Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai 200031, China;4. Shenzhen Key Laboratory of Translational Medicine of Tumor, Department of Cell Biology and Genetics, Shenzhen University Health Sciences Center, Shenzhen, Guangdong 518060, China;5. University of Chinese Academy of Sciences, Beijing 100049, China;6. School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China;1. Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA;2. The University of Texas MD Anderson UTHealth Graduate School of Biomedical Sciences, Houston, TX, USA;1. CAS Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China;2. CAS Key Laboratory of Zoological Systematics and Evolution, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China;3. Center for Excellence in Animal Evolution and Genetics, Chinese Academy of Sciences, Kunming 650223, China
Abstract:
Keywords:VHL  HIF  ccRCC  Kidney cancer  Hypoxia
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