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Changes in N-acetyl-beta-D-glucosaminidase activity in the urine and urinary albumin excretion in magnesium deficient rats
Authors:Matsuzaki Hiroshi  Ohdachi Junko  Fuchigami Masaaki  Masuyama Ritsuko  Uehara Mariko  Nakamura Kahoru  Suzuki Kazuharu
Affiliation:Department of Nutrition, Junior College of Tokyo University of Agriculture, Japan.
Abstract:To discover the details of the effects of magnesium (Mg) deficiency on kidney function, the course of changes in N-acetyl-beta-D-glucosaminidase (NAG) activity in the urine and in urinary albumin excretion were examined in rats fed a Mg-deficient diet. NAG activity in the urine and urinary albumin excretion in rats fed the Mg-deficient diet significantly increased from 7 d until the end of the feeding period. We suggest that Mg-deficient diet rapidly induces kidney function insufficiency.
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