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Adenylate-rich oligonucleotides of ribosomal and ribosomal precursor RNA from HeLa cells
Authors:H.C. BirnboimB.V. Coakley
Affiliation:Biology and Health Physics Division, Chalk River Nuclear Laboratories, Atomic Energy of Canada Limited, Chalk river, Ontario, Canada
Abstract:HeLa cell ribosomal precursor (45S) RNA has been found to contain nucleotide sequences also found in 18S RNA and others found in 28S RNA. Thus, 18S RNA and 28S RNA are readily distinguishable, whereas 45S RNA is similar to 18S and 28S RNA combined. The nucleotide sequences analysed were those resistant to the combined action of pancreatic and T1 ribonucleases.
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