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| 长双歧杆菌完整肽聚糖对小鼠免疫功能的影响 | |
| 引用本文： | 付艳茹,龚虹,刘彦民,李莹,黄少磊. 长双歧杆菌完整肽聚糖对小鼠免疫功能的影响[J]. 中国微生态学杂志, 2010, 22(3): 217-219,222 |
| 作者姓名： | 付艳茹 龚虹 刘彦民 李莹 黄少磊 |
| 作者单位： | 1. 内蒙古轻工科学研究所,内蒙古,呼和浩特,010051 2. 内蒙古双奇药业有限公司,内蒙古,呼和浩特,010010 3. 内蒙古社会科学院,内蒙古,呼和浩特,010010 |
| 摘 要： | 目的比较长双歧杆菌及其完整肽聚糖的免疫调节作用。方法通过研究长双歧杆菌完整肽聚糖对植瘤小鼠淋巴细胞的转化、抑瘤率、生命延长期以及对细胞Bcl-2和Bax表达的影响来探讨它们对小鼠细胞免疫的调节作用。结果与对照组相比,完整肽聚糖使淋巴细胞转化增加、抑瘤率提高、延长生命期增加、Bcl-2阳性表达率减小而Bax基因表达增加。结论长双歧杆菌与其完整肽聚糖均有抑制S180肿瘤的作用,但完整肽聚糖的效果优于长双歧杆菌。 |
| 关 键 词： | 长双歧杆菌 完整肽聚糖 免疫功能 |
Effect of the whole peptidoglycan from Bifidobacterium longum on the immune function of mice |
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| FU Yan-ru,GONG Hong,LIU Yan-min,LI Ying,HUANG Shao-lei. Effect of the whole peptidoglycan from Bifidobacterium longum on the immune function of mice[J]. Chinese Journal of Microecology, 2010, 22(3): 217-219,222 | |
| Authors: | FU Yan-ru GONG Hong LIU Yan-min LI Ying HUANG Shao-lei |
| Affiliation: | FU Yan-ru1,GONG Hong2,LIU Yan-min2,LI Ying3,HUANG Shao-lei2(1.Inner Mongolia Light Industrial Research Institute,Huhhot 010051,China,2.Inner Mongolia ShuangQi Pharmaceutical Co,Ltd.,Huhhot 010010,3 Inner Mongolia Academy of Social Science,China) |
| Abstract: | Objective To compare the immunoregulations of Bifidobacterium longum and its whole peptidoglycan.Method The regulating effect of the whole peptidoglycan of Bifidobacterium longum on the transformation,tumor inhibition rate and life period of the lymphocytes of tumor bearing mice,as well as their affection on the expression of Bcl-2 and Bax were studied to explore their immunoregulation on the cell immune system of mice.Result Compared with the control group,whole peptidoglycan increased the tranformation of... |
| Keywords: | Bifidobacterium longum Whole peptidoglycan Immuniological function |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |