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HIV-1 infection: going nuclear with TNPO3/Transportin-SR2 and integrase
Authors:Luban Jeremy
Affiliation:Department of Microbiology and Molecular Medicine, University of Geneva, CH-1211 Geneva 4, Switzerland. jeremy.luban@unige.ch
Abstract:Factors necessary for HIV-1 nuclear import have been sought for many years. Recent reports suggest that TNPO3/Transportin-SR2 binds to HIV-1 integrase and is required for HIV-1 infection of interphase cells.
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