Study of human allergic milk whey protein from different mammalian species using computational method

Nowadays, safety and quality assessment of food used for human consumption have to consider by its possible contribution to themaintenance or improvement of the consumer''s health. Milk is an important food with many nutrients. Cow milk is an importantsource of energy, protein, vitamins and minerals for the growing child as well as adults. But, numerous cow milk proteins havebeen implicated in allergic responses and most of these have been shown to contain multiple allergic epitopes. The present studydisclosed best alternatives to cow milk, which are not allergic and as good as cow milk in nutritional value. The in silico analysis ofcasein (alpha s1, alpha s2, beta and kappa) and beta-lactoglobulin, unveils that sheep milk is a more suitable alternate to cow milkfor allergic infants and buffalo milk for allergic adult humans.