A concentric layer model for estimating the energy expenditure of the left ventricle |
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Authors: | Alan Y K Wong PhD |
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Institution: | (1) Department of Physiology and Biophysics, Dalhousie University, Halifax, Nova Scotia |
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Abstract: | The energy cost of the left ventricle is quantitatively analyzed on the basis of the following assumptions: (1) The left ventricle
is assumed to be an isotropic, homogeneous elastic, thick, spherical shell. (2) The ventricular wall is made up of a finite
number of thin concentric shells. (3) The energetics of the left ventricle is in accordance with the second law of thermodynamics.
An expression for the work done during ventricular contraction is derived according to the definition of physical work. The
energy liberation during isovolumic contraction is formulated parallel to the concepts of heat production in skeletal muscle
during isometric contraction. This expression gives the total work done per stroke in terms of mean systolic pressure, end
diastolic volume, stroke volume and wall thickness during diastolic phase.
Supported by a research fellowship and research grant from the Canadian Heart Foundation. |
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