ExpressionPlot: a web-based framework for analysis of RNA-Seq and microarray gene expression data |
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| Authors: | Brad A Friedman Tom Maniatis |
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| Affiliation: | (1) Department of Molecular and Cell Biology, Harvard University, 7 Divinity Ave, Cambridge, MA 02138, USA;(2) The Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA;(3) Department of Bioinformatics and Computational Biology, Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, USA;(4) Department of Biochemistry and Molecular Biophysics, Columbia University College of Physicians and Surgeons, 701 West 168th St, New York, NY 10032, USA |
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| Abstract: | RNA-Seq and microarray platforms have emerged as important tools for detecting changes in gene expression and RNA processing in biological samples. We present ExpressionPlot, a software package consisting of a default back end, which prepares raw sequencing or Affymetrix microarray data, and a web-based front end, which offers a biologically centered interface to browse, visualize, and compare different data sets. Download and installation instructions, a user's manual, discussion group, and a prototype are available at . |
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