Comparative genetic mapping of cellular rel sequences in man, mouse, and the domestic cat. |
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| Authors: | E Brownell C A Kozak J R Fowle rd W S Modi N R Rice S J O'Brien |
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| Affiliation: | E Brownell, C A Kozak, J R Fowle, 3rd, W S Modi, N R Rice, and S J O'Brien |
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| Abstract: | We used in situ hybridization techniques to assign the human c-rel locus to the centromere-proximal portion of the short arm of chromosome 2 (2cent-2p13). We also determined the chromosomal location of c-rel sequences in the domestic cat and the laboratory mouse by using a human c-rel fragment to screen panels of rodent X cat and hamster X mouse somatic cell hybrid DNAs. The c-rel locus apparently maintains similar syntenic relationships with other known genetic markers in the human and cat, but displays different linkage relationships in the mouse. |
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