SALMONELLABASE - An online database of druggable targets of Salmonella species |
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Authors: | Ophilia Benedict Pushpa Muthaiyan Xavier Suresh |
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Institution: | Department of Bioinformatics, Sathyabama University, Jeppiaar Nagar, Rajiv Gandhi Salai, Chennai - 600 119 |
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Abstract: | Salmonellosis is one of the most common and widely distributed food borne diseases caused by Salmonella serovars. The
emergence of multi drug resistant strains has become a threatening public health problem and targeting unique effectors of this
pathogen can be considered as a powerful strategy for drug design. SalmonellaBase is an online web portal serving as an integrated
source of information about Salmonella serovars with the data required for the structural and functional studies and the analysis of
druggable targets in Salmonella. We have identified several target proteins, which helps in the pathogenicity of the organism and
predicted their structures. The database will have the information on completely sequenced genomes of Salmonella species with
the complete set of protein sequences of the respective strains, determined structures, predicted protein structures and biochemical
pathways of the respective strains. In addition, we have provided information about name and source of the protein, Uniprot and
Protein Data Bank codes and literature information. Furthermore, SalmonellaBase is linked to related databases and other
resources. We have set up a web interface with different search and display options so that users have the ability to get the data in
several ways. SalmonellaBase is a freely available database.Availabilityhttp://www.salmonellabase.com/ |
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Keywords: | SalmonellaBase Database Drug Design Salmonella Druggable Targets |
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