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Autoregulation of Osteocyte Sema3A Orchestrates Estrogen Action and Counteracts Bone Aging
Authors:Mikihito Hayashi  Tomoki Nakashima  Noriko Yoshimura  Kazuo Okamoto  Sakae Tanaka  Hiroshi Takayanagi
Affiliation:1. Department of Cell Signaling, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo 113-8549, Japan;2. Japan Science and Technology Agency (JST), Precursory Research for Embryonic Science and Technology (PRESTO), Tokyo 113-8549, Japan;3. Japan Agency for Medical Research and Development, Core Research for Evolutional Science and Technology (AMED-CREST), Tokyo 113-8549, Japan;4. Department of Joint Disease Research, 22nd Century Medical and Research Center, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, Tokyo 113-0033, Japan;5. Department of Osteoimmunology, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, Tokyo 113-0033, Japan;6. Department of Orthopedic Surgery, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, Tokyo 113-0033, Japan;7. Department of Immunology, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, Tokyo 113-0033, Japan
Abstract:
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  • Keywords:bone aging  Sema3A  osteocyte
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